The Story of IN8bio

IN8bio was founded with the mission of developing next-generation cellular therapies for treating cancer. Dr. Lawrence Lamb, one the Company’s co-founders, is a leader in the field of gamma-delta T cells. During his postdoctoral fellowship in transplant medicine, he was the first to describe homeostatic reconstitution of gamma-delta T cells in patients who receive alpha-beta T cell depleted bone marrow grafts. Dr. Lamb also identified an association between gamma-delta T cell levels and disease-free survival in allogeneic bone marrow transplantation. This work formed the foundation of IN8bio’s focus on delivering gamma-delta therapeutics for the treatment of cancer. The Company is developing allogeneic, autologous, iPSC and genetically modified gamma-delta T cell therapies. Dr. Lamb’s research has formed the basis for the company’s Phase 1 and Phase 2 clinical trials, two in newly-diagnosed Glioblastoma and one in leukemia and lymphoma patients undergoing hematopoietic bone marrow transplantation. Additionally, the Company is also continuing to explore the application of its technology in additional therapeutic combinations. IN8bio is located in New York City with its primary scientific operations in Birmingham, Alabama.